As the body old age , muscles become more potential to atrophy and less able to rectify speedily , correct ? If nature had its way , yes — but now scientists may have discovered a mode to make old muscle feel younger again .
New research , led by UC Berkeley’sIrina Conboy , has proven that older brawniness does n’t just not oppose well to sudden exercise ( regenerating four clock time slower than young muscle ) , but that it can oppose badly to it , creating scar tissue alternatively of renegerating . As Conroy explains ,
The quondam muscle also did n’t recover as well with exercise … This emphasise the importance of elder universe stay active because the evidence is that for their brawniness , long full stop of disuse may irrevocably worsen the stem jail cell ’ regenerative surround … It ’s like a Catch-22 .

However , the inquiry discovered the creation of an enzyme in the human consistence calledmitogen - activated protein kinase(MAPK ) , which regulates a muscle - growth - trigger off sensory receptor called Notch . In older bodies , MAPK levels were so low that Notch did n’t become active , fit in to Conroy , but as luck would have it science can fix that ; the scientists cultured sometime human muscle in the lab , unnaturally activated MAPK and saw the muscle ’s regenerative ability soar . For Conroy , this find is just the start :
In hard-nosed terms , we now know that to enhance positive feedback of old human brawn and reconstruct tissue health , we can either target the MAPK or the Notch nerve pathway … The ultimate end , of course , is to move this research toward clinical trial .
And then , we hope , kill theaging processaltogether . Or , at least , receive a way to overthrow my manly pattern baldness .

Clock Turned Back on Aging Muscles , Researchers Claim[LiveScience ]
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