To be more specific , hoi polloi ’s immune reply killed them . The virus was especially deadly to vernal and middle - older adults because their immune scheme were prime to kick into a fatal , antiviral overdrive .
One of the factors that scared mass most about the H1N1 influenza was its severity in otherwise healthy adults . Flu viruses are usually serious . Nobody ‘ just ’ has the flu . The 1918 influenza killed more people than World War I. Less baneful strains , though , usually only defeat the very young or the very old . H1N1 did the opposite . Children and honest-to-goodness multitude experienced comparatively mild symptom . vernal to middle aged grownup , on the other bridge player , often die of the sickness .
Doctor Fernando Polack investigate the suit of this turnabout . He found that people often died due to their own body ’s reply to the sickness , rather than the malady itself . When a computer virus obtrude upon the trunk , the eubstance protects itself by do antibody , and by an overall resistant response . Much of the things we associate with being sick , like coughing , and a runny nozzle , are the body ’s immune response trying to toss off the invaders . Antibodies are tailor-make to sicknesses , and are hive away in the body after the unwellness passes .
unseasoned children had not had the flu before , and so did not have antibody . Those old enough to have survived a influenza before 1957 had already been taint by a flu standardized enough to H1N1 to have antibodies that worked . in-between senior multitude who had the influenza before , but not one similar to H1N1 , had antibodies that ‘ recognized ’ the flu , but could do nothing to stop it .
Those middle - ripened people were most at risk . Their bodies needed to make antibodies ‘ from pelf ’ the means fry did . Unlike children , however , their bodies knew something was ill unseasonable so their immune organisation plain into overdrive . It went on the warpath , unleashing protein that killed everything in sight , include its host body . Many people die because their immune organization destroyed their lung in an effort to kill the invader . As yet there is no way to blockade this immune response , though there may be the great unwashed who are more susceptible to it than others .
ViaNature Medicine .
BiologyMedicinePandemicScience
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